1Isaac called Jacob, blessed him, and commanded him, “You shall not take a wife of the daughters of Canaan. 2Arise, go to Paddan Aram, to the house of Bethuel your mother’s father. Take a wife from there from the daughters of Laban, your mother’s brother. 3May God Almighty bless you, and make you fruitful, and multiply you, that you may be a company of peoples, 4and give you the blessing of Abraham, to you and to your offspring with you, that you may inherit the land where you travel, which God gave to Abraham.”
5Isaac sent Jacob away. He went to Paddan Aram to Laban, son of Bethuel the Syrian, the brother of Rebekah, Jacob’s and Esau’s mother.
6Now Esau saw that Isaac had blessed Jacob and sent him away to Paddan Aram, to take him a wife from there, and that as he blessed him he gave him a command, saying, “You shall not take a wife of the daughters of Canaan;” 7and that Jacob obeyed his father and his mother, and was gone to Paddan Aram. 8Esau saw that the daughters of Canaan didn’t please Isaac, his father. 9So Esau went to Ishmael, and took, in addition to the wives that he had, Mahalath the daughter of Ishmael, Abraham’s son, the sister of Nebaioth, to be his wife.
10Jacob went out from Beersheba, and went toward Haran. 11He came to a certain place, and stayed there all night, because the sun had set. He took one of the stones of the place, and put it under his head, and lay down in that place to sleep. 12He dreamed and saw a stairway set upon the earth, and its top reached to heaven. Behold, the angels of God were ascending and descending on it. 13Behold, Yahweh stood above it, and said, “I am Yahweh, the God of Abraham your father, and the God of Isaac. I will give the land you lie on to you and to your offspring. 14Your offspring will be as the dust of the earth, and you will spread abroad to the west, and to the east, and to the north, and to the south. In you and in your offspring, all the families of the earth will be blessed. 15Behold, I am with you, and will keep you, wherever you go, and will bring you again into this land. For I will not leave you until I have done that which I have spoken of to you.”
16Jacob awakened out of his sleep, and he said, “Surely Yahweh is in this place, and I didn’t know it.” 17He was afraid, and said, “How awesome this place is! This is none other than God’s house, and this is the gate of heaven.”
18Jacob rose up early in the morning, and took the stone that he had put under his head, and set it up for a pillar, and poured oil on its top. 19He called the name of that place Bethel, but the name of the city was Luz at the first. 20Jacob vowed a vow, saying, “If God will be with me, and will keep me in this way that I go, and will give me bread to eat, and clothing to put on, 21so that I come again to my father’s house in peace, and Yahweh will be my God, 22then this stone, which I have set up for a pillar, will be God’s house. Of all that you will give me I will surely give a tenth to you.”
Isaac was the son of promise to Abraham and Sarah, and the half-brother of Ishmael (who became the father of the Arab people) and the father of Esau (from whom came the Edomites) and Jacob. Isaac was born of a mother beyond childbearing age by a miracle of Yahweh, and was a focus of the testing of Abraham and Sarah, his parents.
The name Isaac means "to laugh, or he laughs," which is based on the response of Sarah to Yahweh's statement to Abraham that she was to bear a son. Sarah was hiding out of sight when this announcement was made by the Angel of Yahweh, and upon hearing this statement, she laughed, which she denied later before the angel. Such an idea was considered impossible but happened as promised by the heavenly visitor. Later, Abraham's faith was tested when God commanded him to sacrifice his only son, Isaac. He followed through with this command of God but received him back alive, since Yahweh kept him from doing so, declaring that now He knew by experience (see the meaning of Hebrew yada') that Abram did not withhold his son.
Later in Isaac's life, he married Rebekah, who bore him Jacob (biography) and Esau (his favorite), and was tricked by Jacob and Rebekah into giving his younger son Jacob his blessing.
Isaac was the only son of Abraham and Sarah, a half-brother of Ishmael and father of Esau and Jacob. Isaac was born when both of his parents were very old, the circumstances surrounding his birth being a test of their faith. The meaning of Isaac's name (“he laughs”) is explained by the fact that Abraham laughed when he was told a son would be born to him at the age of a hundred. Abraham's faith was further tested when he was told to sacrifice Isaac but was stopped at the last moment from carrying out this instruction.
See also Biographies of Bible Characters, People and Characters in the Bible.