1After these things, God tested Abraham, and said to him, “Abraham!”
He said, “Here I am.”
2He said, “Now take your son, your only son, Isaac, whom you love, and go into the land of Moriah. Offer him there as a burnt offering on one of the mountains which I will tell you of.”
3Abraham rose early in the morning, and saddled his donkey; and took two of his young men with him, and Isaac his son. He split the wood for the burnt offering, and rose up, and went to the place of which God had told him. 4On the third day Abraham lifted up his eyes, and saw the place far off. 5Abraham said to his young men, “Stay here with the donkey. The boy and I will go over there. We will worship, and come back to you.” 6Abraham took the wood of the burnt offering and laid it on Isaac his son. He took in his hand the fire and the knife. They both went together. 7Isaac spoke to Abraham his father, and said, “My father?”
He said, “Here I am, my son.”
He said, “Here is the fire and the wood, but where is the lamb for a burnt offering?”
8Abraham said, “God will provide himself the lamb for a burnt offering, my son.” So they both went together. 9They came to the place which God had told him of. Abraham built the altar there, and laid the wood in order, bound Isaac his son, and laid him on the altar, on the wood. 10Abraham stretched out his hand, and took the knife to kill his son.
11Yahweh’s angel called to him out of the sky, and said, “Abraham, Abraham!”
He said, “Here I am.”
12He said, “Don’t lay your hand on the boy or do anything to him. For now I know that you fear God, since you have not withheld your son, your only son, from me.”
13Abraham lifted up his eyes, and looked, and saw that behind him was a ram caught in the thicket by his horns. Abraham went and took the ram, and offered him up for a burnt offering instead of his son. 14Abraham called the name of that place “Yahweh Will Provide”. As it is said to this day, “On Yahweh’s mountain, it will be provided.”
15Yahweh’s angel called to Abraham a second time out of the sky, 16and said, “‘I have sworn by myself,’ says Yahweh, ‘because you have done this thing, and have not withheld your son, your only son, 17that I will bless you greatly, and I will multiply your offspring greatly like the stars of the heavens, and like the sand which is on the seashore. Your offspring will possess the gate of his enemies. 18All the nations of the earth will be blessed by your offspring, because you have obeyed my voice.’”
19So Abraham returned to his young men, and they rose up and went together to Beersheba. Abraham lived at Beersheba.
20After these things, Abraham was told, “Behold, Milcah, she also has borne children to your brother Nahor: 21Uz his firstborn, Buz his brother, Kemuel the father of Aram, 22Chesed, Hazo, Pildash, Jidlaph, and Bethuel.” 23Bethuel became the father of Rebekah. These eight Milcah bore to Nahor, Abraham’s brother. 24His concubine, whose name was Reumah, also bore Tebah, Gaham, Tahash, and Maacah.
Isaac was the son of promise to Abraham and Sarah, and the half-brother of Ishmael (who became the father of the Arab people) and the father of Esau (from whom came the Edomites) and Jacob. Isaac was born of a mother beyond childbearing age by a miracle of Yahweh, and was a focus of the testing of Abraham and Sarah, his parents.
The name Isaac means "to laugh, or he laughs," which is based on the response of Sarah to Yahweh's statement to Abraham that she was to bear a son. Sarah was hiding out of sight when this announcement was made by the Angel of Yahweh, and upon hearing this statement, she laughed, which she denied later before the angel. Such an idea was considered impossible but happened as promised by the heavenly visitor. Later, Abraham's faith was tested when God commanded him to sacrifice his only son, Isaac. He followed through with this command of God but received him back alive, since Yahweh kept him from doing so, declaring that now He knew by experience (see the meaning of Hebrew yada') that Abram did not withhold his son.
Later in Isaac's life, he married Rebekah, who bore him Jacob (biography) and Esau (his favorite), and was tricked by Jacob and Rebekah into giving his younger son Jacob his blessing.
Isaac was the only son of Abraham and Sarah, a half-brother of Ishmael and father of Esau and Jacob. Isaac was born when both of his parents were very old, the circumstances surrounding his birth being a test of their faith. The meaning of Isaac's name (“he laughs”) is explained by the fact that Abraham laughed when he was told a son would be born to him at the age of a hundred. Abraham's faith was further tested when he was told to sacrifice Isaac but was stopped at the last moment from carrying out this instruction.
See also Biographies of Bible Characters, People and Characters in the Bible.